SCUD (Saccharomyces Cerevisiae Ubiquitination Database)

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Wild-type Information
Standard nameSTE6
Systematic nameYKL209C
DescriptionMating factor A secretion protein STE6
Cross references Swiss-Prot accessionP12866

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1  UBC6, UBC7RINGSPRFSSM4  Proteasomal degradation
* Blank: not determined, NA: not applicable.

Reference"Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control."
Vashist S, Ng DT.
J Cell Biol. 165(1):41-52 (2004) [15078901]

"Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein."
Huyer G, Piluek WF, Fansler Z, Kreft SG, Hochstrasser M, Brodsky JL, Michaelis S.
J Biol Chem. 279(37):38369-78 (2004) [15252059]