SCUD (Saccharomyces Cerevisiae Ubiquitination Database)

Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Wild-type Information
Standard namePDR5
Systematic nameYOR153W
AliasLEM1, YDR1, STS1
DescriptionPleiotropic ABC efflux transporter of multiple drugs
Cross references Swiss-Prot accessionP33302

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTIUBC6, UBC7RINGSPRFHRD1  Proteasomal degradation
* Blank: not determined, NA: not applicable.

Reference"Endoplasmic reticulum degradation. Reverse protein transport and its end in the proteasome."
Plemper RK, Wolf DH.
Mol Biol Rep. 26(1-2):125-30 (1999) [10363658]

"Expression and degradation of the cystic fibrosis transmembrane conductance regulator in Saccharomyces cerevisiae."
Kiser GL, Gentzsch M, Kloser AK, Balzi E, Wolf DH, Goffeau A, Riordan JR.
Arch Biochem Biophys. 390(2):195-205 (2001) [11396922]

"Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast."
Gnann A, Riordan JR, Wolf DH.
Mol Biol Cell. 15(9):4125-35 (2004) [15215312]