SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Systematic nameYLR224W
DescriptionF-box protein and component of SCF ubiquitin ligase complexes involved in ubiquitin-dependent protein catabolism; readily monoubiquitinated in vitro by SCF-Ubc4 complexes; YLR224W is not an essential gene.

Ubiquitination Features
Num. of substrates Total 1 wild-type known substrates.
Wild-type substrate
KeywordDescription
YLR224WF-box protein YLR224W

Cross References
Swiss-Prot accessionQ05947
SGD YLR224W
Gene Ontology (GO)
Cellular componentGO:0000151ubiquitin ligase complexIPI:SGD.
Molecular functionGO:0005515protein bindingIPI:SGD.
Biological processGO:0006511ubiquitin-dependent protein catabolic processIPI:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length369
Molecular weight42754

	---------+----------+----------+----------+----------+
MNQSDSSLMD LPLEIHLSLL EYVPNELRAV NKYFYVLHNH SYKEKSLAWI   50
AEDNYIWAVV KHSLCLYVKS LDPLRQHARE IIQETKEPGF NVPLCMTKYI   100
ADSWYIVYNA LQYPGKIINM GWDKYTKSQD SNGSDSTSNF NSRPKERTLM   150
QSLTALPVNF WSRRKDEPTP VNVWFYVKNA HVARYIPKII TEIGICNYGP   200
KQIVASAGYI NELITSEGIY CVNLGHLPRL YDEQIFEGTG TTHLPLELKA   250
IDRTDSDVCI NGDLVLLGYD FIPYQISKPW LLFRIEPVNS IEAIFNYSEC   300
SFSYQFAWSL ACLQSEEKIS FPRDTIIGHG LPYKPSKLIR IFVYKHPEQK   350
QDLGQEIALP NWNTPYLRR                                     369