SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameRAD7
Systematic nameYJR052W
DescriptionProtein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex.

Ubiquitination Features
Num. of substrates Total 1 wild-type known substrates.
Wild-type substrate
KeywordDescription
RAD4DNA repair protein RAD4

Cross References
Swiss-Prot accessionP06779
SGD YJR052W
Gene Ontology (GO)
Cellular componentGO:0031463Cul3-RING ubiquitin ligase complexIDA:SGD.
Cellular componentGO:0000113nucleotide-excision repair factor 4 complexIDA:SGD.
Cellular componentGO:0000108repairosomeIDA:SGD.
Biological processGO:0000715nucleotide-excision repair, DNA damage reco...IDA:SGD.
Biological processGO:0042787protein ubiquitination during ubiquitin-dep...IMP:SGD.
EC number

Additional Features
Post Translational Modifications (PTM)
Residue indexType
107Phosphoserine.

Sequence Information
Sequence length565
Molecular weight63777

	---------+----------+----------+----------+----------+
MYRSRNRPKR GGENEVKGPN SALTQFLREE GISAENIKQK WYQRQSKKQE   50
DATDEKKGKA EDDSFTAEIS RVVEDEEIDE IGTGSGTETE RAQVSYDARM   100
KLVPADSDEE EYETSHISDT PVSLSSANDR ESLTKKRQNT AKIIQNRRRK   150
RKRAADLLDR RVNKVSSLQS LCITKISENI SKWQKEADES SKLVFNKLRD   200
VLGGVSTANL NNLAKALSKN RALNDHTLQL FLKTDLKRLT FSDCSKISFD   250
GYKTLAIFSP HLTELSLQMC GQLNHESLLY IAEKLPNLKS LNLDGPFLIN   300
EDTWEKFFVI MKGRLEEFHI SNTHRFTDKS LSNLLINCGS TLVSLGLSRL   350
DSISNYALLP QYLVNDEFHS LCIEYPFNEE DVNDEIIINL LGQIGRTLRK   400
LVLNGCIDLT DSMIINGLTA FIPEKCPLEV LSLEESDQIT TDSLSYFFSK   450
VELNNLIECS FRRCLQLGDM AIIELLLNGA RDSLRSLNLN SLKELTKEAF   500
VALACPNLTY LDLGFVRCVD DSVIQMLGEQ NPNLTVIDVF GDNLVTEKAT   550
MRPGLTLIGR QSDSI                                         565