SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Enzyme Information

General Information
Standard nameRAD18
Systematic nameYCR066W
DescriptionProtein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif.

Ubiquitination Features
Num. of substrates Total 2 wild-type known substrates.
Wild-type substrate
KeywordDescription
HOHomothallic switching endonuclease
POL30Proliferating cell nuclear antigen

Cross References
Swiss-Prot accessionP10862
SGD YCR066W
Gene Ontology (GO)
Cellular componentGO:0000790nuclear chromatinIDA:SGD.
Molecular functionGO:0008094DNA-dependent ATPase activityIDA:SGD.
Molecular functionGO:0003697single-stranded DNA bindingIDA:SGD.
Molecular functionGO:0004842ubiquitin-protein ligase activityIDA:SGD.
Biological processGO:0006301postreplication repairIMP:SGD.
EC number 6.3.2.-

Additional Features
Post Translational Modifications (PTM)
Residue indexType
155Phosphothreonine.
174Phosphoserine.
181Phosphoserine.

Sequence Information
Sequence length487
Molecular weight55230

	---------+----------+----------+----------+----------+
MDHQITTASD FTTTSIPSLY QLDTLLRCHI CKDFLKVPVL TPCGHTFCSL   50
CIRTHLNNQP NCPLCLFEFR ESLLRSEFLV SEIIQSYTSL RSSLLDALRI   100
PKPTPVPENE EVPGPENSSW IELISESESD SVNAADDDLQ IVATSERKLA   150
KRSMTDILPL SSKPSKRNFA MFRSERIKKK SKPNEQMAQC PICQQFYPLK   200
ALEKTHLDEC LTLQSLGKKP KISTTFPTES NPHNKSSSRF KVRTPEVDKS   250
SCGETSHVDK YLNSMMSAEH QRLPKINFTS MTQSQIKQKL SSLGLSTNGT   300
RQNMIKRYNH YEMLWNSNFC DSLEPVDEAE LKRQLLSWDV SHNKTPQNSS   350
NKGGISKLMI MKSNGKSSSY RKLLENFKND KFNRKGWMVM FRKDFARLIR   400
EAKMKIKTGS SDSSGSVGHS NDGDGVEKVQ SDQGTEDQQM EKDQDTVINE   450
DRVAGERNLP NEDSTDADLS RELMDLNEYS KDPPGNN                 487