SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard namePRP19
Systematic nameYLL036C
AliasPSO4
DescriptionSplicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases.

Ubiquitination Features
Num. of substrates Total 0 wild-type known substrates.

Cross References
Swiss-Prot accessionP32523
SGD YLL036C
Gene Ontology (GO)
Cellular componentGO:0005739mitochondrionIDA:SGD.
Cellular componentGO:0005681spliceosomeIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0031202RNA splicing factor activity, transesterifi...IMP:SGD.
Biological processGO:0000398nuclear mRNA splicing, via spliceosomeIDA:SGD.
Biological processGO:0006511ubiquitin-dependent protein catabolic processIPI:SGD.
EC number

Additional Features
Post Translational Modifications (PTM)
Residue indexType
141Phosphoserine, by ATM or ATR.

Sequence Information
Sequence length503
Molecular weight56570

	---------+----------+----------+----------+----------+
MLCAISGKVP RRPVLSPKSR TIFEKSLLEQ YVKDTGNDPI TNEPLSIEEI   50
VEIVPSAQQA SLTESTNSAT LKANYSIPNL LTSLQNEWDA IMLENFKLRS   100
TLDSLTKKLS TVMYERDAAK LVAAQLLMEK NEDSKDLPKS SQQAVAITRE   150
EFLQGLLQSS RDFVARGKLK APKWPILKNL ELLQAQNYSR NIKTFPYKEL   200
NKSMYYDKWV CMCRCEDGAL HFTQLKDSKT ITTITTPNPR TGGEHPAIIS   250
RGPCNRLLLL YPGNQITILD SKTNKVLREI EVDSANEIIY MYGHNEVNTE   300
YFIWADNRGT IGFQSYEDDS QYIVHSAKSD VEYSSGVLHK DSLLLALYSP   350
DGILDVYNLS SPDQASSRFP VDEEAKIKEV KFADNGYWMV VECDQTVVCF   400
DLRKDVGTLA YPTYTIPEFK TGTVTYDIDD SGKNMIAYSN ESNSLTIYKF   450
DKKTKNWTKD EESALCLQSD TADFTDMDVV CGDGGIAAIL KTNDSFNIVA   500
LTP                                                      503