SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameMET30
Systematic nameYIL046W
AliasZRG11
DescriptionF-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus.

Ubiquitination Features
Num. of substrates Total 2 wild-type known substrates.
Wild-type substrate
KeywordDescription
MET4Transcriptional activator of sulfur metabolism MET4
SWE1Mitosis inhibitor protein kinase SWE1

Cross References
Swiss-Prot accessionP39014
SGD YIL046W
Gene Ontology (GO)
Cellular componentGO:0043224nuclear SCF ubiquitin ligase complexIDA:SGD.
Molecular functionGO:0042802identical protein bindingIPI:IntAct.
Biological processGO:0007049cell cycleTAS:SGD.
Biological processGO:0016567protein ubiquitinationIGI:SGD.
Biological processGO:0046685response to arsenicIDA:SGD.
Biological processGO:0046686response to cadmium ionIDA:SGD.
Biological processGO:0031146SCF-dependent proteasomal ubiquitin-depende...IDA:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length640
Molecular weight72835

	---------+----------+----------+----------+----------+
MRRERQRMMS FEDKDKDDLD NSNSNNSSEM TDTAMMPPLK RLLITGSSDD   50
LAQGSSGKKK MTMATRSPSS SPDLATNDSG TRVQPLPEYN FTKFCYRHNP   100
DIQFSPTHTA CYKQDLKRTQ EINANIAKLP LQEQSDIHHI ISKYSNSNDK   150
IRKLILDGIL STSCFPQLSY ISSLVTHMIK IDFISILPQE LSLKILSYLD   200
CQSLCNATRV CRKWQKLADD DRVWYHMCEQ HIDRKCPNCG WGLPLLHMKR   250
ARIQQNSTGS SSNADIQTQT TRPWKVIYRE RFKVESNWRK GHCRIQEFKG   300
HMDGVLTLQF NYRLLFTGSY DSTIGIWDLF TGKLIRRLSG HSDGVKTLYF   350
DDRKLITGSL DKTIRVWNYI TGECISTYRG HSDSVLSVDS YQKVIVSGSA   400
DKTVKVWHVE SRTCYTLRGH TEWVNCVKLH PKSFSCFSCS DDTTIRMWDI   450
RTNSCLKVFR GHVGQVQKII PLTIKDVENL ATDNTSDGSS PQDDPTMTDG   500
ADESDTPSNE QETVLDENIP YPTHLLSCGL DNTIKLWDVK TGKCIRTQFG   550
HVEGVWDIAA DNFRIISGSH DGSIKVWDLQ SGKCMHTFNG RRLQRETQHT   600
QTQSLGDKVA PIACVCIGDS ECFSGDEFGC VKMYKFDLND               640