SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Enzyme Information

General Information
Standard nameMDM30
Systematic nameYLR368W
AliasDSG1
DescriptionF-box protein; physically associates with mitochondria and is required for normal mitochondrial fusion in rich medium, during sporulation, and in mating cells; promotes ubiquitin-mediated degradation of Gal4p in some strains.

Ubiquitination Features
Num. of substrates Total 2 wild-type known substrates.
Wild-type substrate
KeywordDescription
FZO1Transmembrane GTPase FZO1
GAL4Regulatory protein GAL4

Cross References
Swiss-Prot accessionQ05930
SGD YLR368W
Gene Ontology (GO)
Cellular componentGO:0005739mitochondrionIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0008053mitochondrial fusionIMP:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length598
Molecular weight70528

	---------+----------+----------+----------+----------+
MTKRRNLFMV GSSFTIDHLP PEIWLCISKL VGTSDLHNLC LINRRLYLTI   50
TSDEIWKRRC YDRWINRESL DILTGNDYDS IPVSQWYSYY LRRAKWENKI   100
FCLLWGLTEE TNPQHFREKY LHILQFRHYK LATFLHRIIK QGYIPDKRPL   150
DLITYANYLL KNVRHKYVFP LFYPTNAAEL KNLNNMASRD AEMIYLRLSA   200
IDTSFDDLLD AREFILNGIC SDLLQKYKKI EEFLKLRPVT RVSKLISIST   250
DYLDCFTQPH DSVGQTNDRA TGRELHREDF MLLRVYSREG RGYKTIILAI   300
IQAITKRYNV DSYLARDHLV VSEPDFPDGR AFVTVNEDFQ PYIFDKEDLL   350
SVWSNNFHNA ENFESTVLPA LLEPISIQHL LTEFFRELLR CKPRPFEGYP   400
NRAHGLRDMF PYGKVEVPRD VTMYFAFIYD LFDGMFESGM TSLRGQMLRD   450
LLNYVNANNF GDLNIIIGQN ALKEPNDCWS NKRDYVLLDD NNKIGYFYTD   500
IETEDTLCAL NQYEVDGKVF ITTIDILGDI RVRLAEGLTP FQGDNDKLWE   550
SFSSVVPRTD WGLFFKGYDK ERRRMQLNPY IEEKLSNLAN DEQPLHNL     598