SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameELA1
Systematic nameYNL230C
DescriptionElongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex.

Ubiquitination Features
Num. of substrates Total 1 wild-type known substrates.
Wild-type substrate
KeywordDescription
RPB1DNA-directed RNA polymerase II subunit RPB1

Cross References
Swiss-Prot accessionP53861
SGD YNL230C
Gene Ontology (GO)
Cellular componentGO:0031463Cul3-RING ubiquitin ligase complexIMP:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0042787protein ubiquitination during ubiquitin-dep...IMP:SGD.
EC number

Additional Features
Post Translational Modifications (PTM)
Residue indexType
278Phosphoserine.

Sequence Information
Sequence length379
Molecular weight43981

	---------+----------+----------+----------+----------+
MKSLQTLCEI SLMRNHSNIQ SVSNVPYHLL KRILQKVKIP QLLKLEKSNV   50
LLIFDDDELW LEFLRQDFPT NVHEQFVSKR DIICKYYFDF VKENDIELYH   100
SNQDLLKSCV RQSVVKDIRN NKYRIPYRML YSKYQQEVEK KQEESAERLR   150
LEMQKLQQER EKKQTIVVDH TVYFKKRNTK KTTRLHNEPH SQLYMKSLKD   200
HESRLKHFKD GGFNIAKRHA QRVAFGGQAG GQSSSPKKGP LSIKPEPVKV   250
NRQMDNVTAE KKDVTQPITP VKKRRSESPS IFLNRKKPAL FRPTPKTNAA   300
GSRPHTTAIT NDHRTTSHPY PHKDVVTSIS SVTANPVTKG HKKKKSGIFV   350
RNAGSDGDSF PHVTATGPTT RPYIYEPRK                          379