SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameDIA2
Systematic nameYOR080W
AliasYOR29-31
DescriptionOrigin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth.

Ubiquitination Features
Num. of substrates Total 1 wild-type known substrates.
Wild-type substrate
KeywordDescription
TEC1Ty transcription activator TEC1

Cross References
Swiss-Prot accessionQ08496
SGD YOR080W
Gene Ontology (GO)
Cellular componentGO:0019005SCF ubiquitin ligase complexIDA:SGD.
Molecular functionGO:0003688DNA replication origin bindingIPI:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006260DNA replicationIMP:SGD.
Biological processGO:0001403invasive growth (sensu Saccharomyces)IGI:SGD.
Biological processGO:0016567protein ubiquitinationIMP:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length746
Molecular weight86801

	---------+----------+----------+----------+----------+
MSYKFITKNK KYTPMSSPGN SGVAIDSTVL KAIELGTRLF KSGEYLQAKR   50
IFTNALRVCD SYSQEQIMRI RNAYQLDTAR PDNKRLYHPR YIKILDNICA   100
CYEKLNDLKS CLDVSQRLLK LEPGNIKCYI RCTRTLIKLK DWKRAYKTCS   150
RGLQLCNNDS NHLRQQKQFI KNNMVQKQDG KRSYIDPLEE TKIAKKKKNN   200
NVLESLPKKK IKGSTKKTDL VGNLPIEILP IIFQRFTTKE LVTLSLVCNK   250
WRDKILYHLD CFQEFNLAPI NFKNFVKFMD FLQQNFTRTY RKYILSQVKV   300
SSRITSEELR ITQLLFSKMP KCINIERLIL SMPTLTTTQI FKLMVRGGTD   350
FFTRLLELSL MITYRPDKQH ELEILQTCPL LKKIELIFVN SLVPIFDGNN   400
SVGRDGSFNV MARHTNMQIS TADNDEQGIV EEKVIYSELE KITLICDKKK   450
IKNFPLCRAL LRGQFPLLQK LTITGVTFPM NNQDIMNFQW LLNFPDLKEL   500
WIEDNDNCEL SKFLQLLKFS NVWKNLEKLT FRENKLYPIV NLDEDQPVTN   550
DDEVPSMLFY KENLQNLEKL DLMGTSISGS ALTRLCEQEY LDGRKLRSLN   600
IGNCPNIQFP NNHAHTARMI LDVNAVLKRL SKLEEINLSH LSSLNDSTMK   650
SFIINVPFLE NLKRLDISHN FEITGISIYE FLKKFQMDHD NEAGGQPLAY   700
LNIDGCSQVS HITVNMIRAQ NLVTQVDCVY ERDVWRKFGI NSYSYS       746