SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameASI3
Systematic nameYNL008C
DescriptionPutative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals.

Ubiquitination Features
Num. of substrates Total 0 wild-type known substrates.

Cross References
Swiss-Prot accessionP53983
SGD YNL008C
Gene Ontology (GO)
Cellular componentGO:0005789endoplasmic reticulum membraneIGI:SGD.
Cellular componentGO:0005637nuclear inner membraneIDA:SGD.
Molecular functionGO:0004842ubiquitin-protein ligase activityIGI:SGD.
Biological processGO:0006511ubiquitin-dependent protein catabolic processIGI:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length669
Molecular weight76741

	---------+----------+----------+----------+----------+
MLSNCSITRD VFSFFHNKTG NLNYLDNTTQ KPEVFVSPNS TIVSAPTLDS   50
FQALMEKGNF TTLQLAKVGI RMFFSYSVSK YAVLCFSTAI ILNRLTVMSS   100
LRSNSTNIRL PLWSKTLLHL VATLSLVKAL LQILSQFGLM HELHVSDTDF   150
YALSVYLFVA LSDCIEIFIS STTNVPSLIC SDFSIWGLSL NLYIISKMPA   200
GQQHIGDNVE LLGAVFHRLV IHLVELFHIR AYRLCGEVIL NAGFFTAFVT   250
RTYLNGLDFI NICLIHNYFP GFFYISTILL ASIGIFLKAL FTSNPFRSLY   300
SRYKNLEKWW RSNNYNGEEE FNEIALSLCL LLTSNDYKIF KKSDNVKSVD   350
EVAAFSNSYV VSGHLNQLQS TPEDLLSRKE MTTDSQLPGF ARTYLGLFEL   400
VRTIILTYSR LLKNLLWSKN FESSIDKKPR VGKRKKRDLN KYVTEKNYKK   450
FLYKPDVKEL NIESDLRSLE LLLPEDDSSK DYFPPRKIDE SVSDEEFDSD   500
MESQLIIDEE KELTHLSSNA VDSDDLEEIA WNISMWSILN YEMDVHNKVN   550
GPLTRSQYGK RNPQGVLVDV VIERLLHHTN SRYMYKRLNM KDDDKLEFKF   600
DFAFDSCDEV EEMDLSCLIC KVNKRNIVTW PCRCLALCDD CRISLGYKGF   650
ATCVSCDSEV KGYSKLNIV                                     669