SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameASI1
Systematic nameYMR119W
DescriptionPutative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals.

Ubiquitination Features
Num. of substrates Total 0 wild-type known substrates.

Cross References
Swiss-Prot accessionP54074
SGD YMR119W
Gene Ontology (GO)
Cellular componentGO:0005789endoplasmic reticulum membraneIGI:SGD.
Cellular componentGO:0005637nuclear inner membraneIDA:SGD.
Molecular functionGO:0004842ubiquitin-protein ligase activityIGI:SGD.
Biological processGO:0006511ubiquitin-dependent protein catabolic processIGI:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length624
Molecular weight71444

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MNSSTSSENV FINSFSYLNQ TSQAVISGNS TFANVINFPY RLGLSFIGAV   50
NLQYEQTVKS EEIPPTLRSV FDTIGFFFSP YAIFCFVIAI VLNRFVVFYA   100
VLNNGSRRTL PLWLSNVFHV SAVVVLAMVS LGPLTLGKDF KILGDPAFAQ   150
EKFLLNIFYA FAYSYCVETI FTIMRNSSPL EGTDYSLFEL SIQFYTMTNN   200
NTKFLDSPDY IIDCSMAILS RILIHLVEIF RLRNYRLLFS TIMNLCHICY   250
LGIRVKQGGW KSLPFSVKFR HFPKLFSVSI ICLSLLIFKL SCLIRWDPFG   300
KSRNSCELLQ FYPLSRNWKK YLNYTGEEDF SAMATKFALL LCSGTELMEK   350
GIRREFPAIN IPDNVNEKFF ISGYLNELSK PYKENTSISF PKKNSSILKQ   400
RFFLMFPKSI IWIMKKLVGQ VFFGFRDNKD EDIPDNDPSK MLKITKTNSL   450
NNSAGHKEDI ELELLNTSDD EYSEDYEPSE VESLGDSDEE NLEEDSLIFN   500
ETRDALLDLF SSEDNEVHTD YNWIMSTSRI LQQKLLSDKT LTRASILDTK   550
LSEVDETFGT ESDFDLSCAV CKVNERNTVL WPCRCFAICE DCRISLGLRG   600
FSTCVCCRSK VHGYCKVHPV SDSK                               624