SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameAMA1
Systematic nameYGR225W
AliasSPO70
DescriptionActivator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis.

Ubiquitination Features
Num. of substrates Total 3 wild-type known substrates.
Wild-type substrate
KeywordDescription
CLB1G2/mitotic-specific cyclin-1
CLB5S-phase entry cyclin-5
PDS1Securin

Cross References
Swiss-Prot accessionP50082
SGD YGR225W
Gene Ontology (GO)
Cellular componentGO:0005680anaphase-promoting complexIPI:SGD.
Molecular functionGO:0008047enzyme activator activityIMP:SGD.
Biological processGO:0007127meiosis IIEP:SGD.
Biological processGO:0030163protein catabolic processIMP:SGD.
Biological processGO:0030476spore wall assembly (sensu Fungi)IMP:SGD.
EC number

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length593
Molecular weight67027

	---------+----------+----------+----------+----------+
MATPHLYHRY NSKSSNKNIN SSGNSTEVDR FIPKSVSRNA YKSIPMLNGF   50
DISYSELCEK SPSPERLSSP EFFNELRNTG HYESISTTNE FSMSSISSSS   100
ESQVTRSGSA RASRNDYSKL TKEQKDHRKN IAHSLGFQLP DRVFTFETTS   150
AEILEKNKAI KNCFGPGSCA EIRSTFDFST LSPDVARYYI ANSNARSASP   200
QRQIQRPAKR VKSHIPYRVL DAPCLRNDFY SNLISWSRTT NNVLVGLGCS   250
VYIWSEKEGA VSILDHQYLS EKRDLVTCVS FCPYNTYFIV GTKFGRILLY   300
DQKEFFHSSN TNEKEPVFVF QTESFKGICC LEWFKPGEIC KFYVGEENGN   350
VSLFEIKSLH FPIKNWSKRQ KLEDENLIGL KLHSTYQAQA QQVCGISLNE   400
HANLLAVGGN DNSCSLWDIS DLDKPIKKFV LPHKAAVKAI AFCPWSKSLL   450
ATGGGSKDRC IKFWHTSTGT LLDEICTSGQ VTSLIWSLRH KQIVATFGFG   500
DTKNPVLITL YSYPKLSKLL EVRSPNPLRV LSAVISPSSM AICVATNDET   550
IRFYELWNDK EEIINEIQES GIYGSNIIEY MEGIETTHNK RIR          593