SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameUBP8
Systematic nameYMR223W
DescriptionUbiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B.

Ubiquitination Features
Num. of substrates Total 1 wild-type known substrates.
Wild-type substrate
KeywordDescription
HTB2Histone H2B.2

Cross References
Swiss-Prot accessionP50102
SGD YMR223W
Gene Ontology (GO)
Cellular componentGO:0000124SAGA complexIDA:SGD.
Molecular functionGO:0004843ubiquitin-specific protease activityTAS:SGD.
Biological processGO:0016579protein deubiquitinationTAS:SGD.
EC number 3.1.2.15

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length471
Molecular weight53623

	---------+----------+----------+----------+----------+
MSICPHIQQV FQNEKSKDGV LKTCNAARYI LNHSVPKEKF LNTMKCGTCH   50
EINSGATFMC LQCGFCGCWN HSHFLSHSKQ IGHIFGINSN NGLLFCFKCE   100
DYIGNIDLIN DAILAKYWDD VCTKTMVPSM ERRDGLSGLI NMGSTCFMSS   150
ILQCLIHNPY FIRHSMSQIH SNNCKVRSPD KCFSCALDKI VHELYGALNT   200
KQASSSSTST NRQTGFIYLL TCAWKINQNL AGYSQQDAHE FWQFIINQIH   250
QSYVLDLPNA KEVSRANNKQ CECIVHTVFE GSLESSIVCP GCQNNSKTTI   300
DPFLDLSLDI KDKKKLYECL DSFHKKEQLK DFNYHCGECN STQDAIKQLG   350
IHKLPSVLVL QLKRFEHLLN GSNRKLDDFI EFPTYLNMKN YCSTKEKDKH   400
SENGKVPDII YELIGIVSHK GTVNEGHYIA FCKISGGQWF KFNDSMVSSI   450
SQEEVLKEQA YLLFYTIRQV N                                  471