SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Enzyme Information

General Information
Standard nameUBP10
Systematic nameYNL186W
AliasDOT4
DescriptionUbiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus.

Ubiquitination Features
Num. of substrates Total 0 wild-type known substrates.

Cross References
Swiss-Prot accessionP53874
SGD YNL186W
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0004843ubiquitin-specific protease activityIDA:SGD.
Biological processGO:0006348chromatin silencing at telomereIMP:SGD.
Biological processGO:0016579protein deubiquitinationIDA:SGD.
EC number 3.1.2.15

Additional Features
Post Translational Modifications (PTM) PTM sites are not determined.

Sequence Information
Sequence length792
Molecular weight88517

	---------+----------+----------+----------+----------+
MTTQESIKPL VDRILSNPLQ FNAAMISNKS NNNDTSAAPE NSSYIVIGKQ   50
HNNNSNSTAI AATAESKQIK ENNLIDRPNG KKTNTVPKSM AEALLLYTSK   100
NDKDAADATG AKKSAELSTE LSTEPPSSSS EDDKVGKEEE EEGEIFHEAR   150
DYVEPRKASL KERDNADKGD GEDIGEDIGE DIGEDIGEDI GEDIGENLGS   200
PLATIDDSSN ENEKEKRKEL STSISSDDEI EDDEDEDDMD YDSSAMEKEL   250
PEEEENDSSS KISEGEKKSL YQDLMENSTV EVNRYEPVNN TKENGNRNPK   300
GEEEEEEEED LKHKSRSITP PVTISNLSNF YQFNENINDR GSLNSTRIVK   350
NWGDKFTNLK PRGLLNHGVT CYTNAAVQAM LHIPSIQHYL FDILMGKYDS   400
TISKNSVSYT LAETSKKMWL PVSKNPRKNV SASYINPKHL ISRLDDINCM   450
MSEWQQEDSH EYFMSLMSRL QEDSVPKGHK LIESIIYDIF GGLLKQIVTC   500
KSCGSISKTE QPFYDLSLHL KGKKKLDPNS DLSSDSINGT SATTSTTTSN   550
AATKPSLSSS SSVNLNNGSP FAAASDLSSA NRRFSIEKSI KDFFNPELIK   600
VDKEQKGYVC EKCHKTTNAV KHSSILRAPE TLLVHLKKFR FNGTSSSKMK   650
QAVSYPMFLD LTEYCESKEL PVKYQLLSVV VHEGRSLSSG HYIAHCKQPD   700
GSWATYDDEY INIISERDVL KEPNAYYLLY TRLTPKSVPL PLAKSAMATG   750
NVTSKSKQEQ AVNEPNNRPL KINSKKNNRK KWKKNKKRKF TK           792