SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Systematic nameYPL146C
DescriptionUncharacterized protein YPL146C

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   HECTNARSP5   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
Methodprotein microarray (in vitro)
Reference"Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast."
Gupta R, Kus B, Fladd C, Wasmuth J, Tonikian R, Sidhu S, Krogan NJ, Parkinson J, Rotin D.
Mol Syst Biol. 3:116 (2007) [17551511]

Cross References
Swiss-Prot accessionQ12080
SGD YPL146C
Gene Ontology (GO)
Cellular componentGO:0005730nucleolusIDA:SGD.
Molecular functionGO:0019843rRNA bindingIDA:SGD.
Biological processGO:0030489processing of 27S pre-rRNAIMP:SGD.
Biological processGO:0000055ribosomal large subunit export from nucleusIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
31Phosphoserine.

Sequence Information
Sequence length455
Molecular weight52556

	---------+----------+----------+----------+----------+
MAPTNLTKKP SQYKQSSRKG KKAWRKNIDL SDVEQYMEKK IDHEITHGTS   50
DITSLQNDAL FHVDVEGDEI LKNKLIKRKQ IKKVLKSKEI LDAVKTNSKI   100
AALNHHKNSS GNPNKIQGVS KHELKKLMAL AGRVHGESKI KNRVAKDGLV   150
KTTAGDLWGE ESNSKKQKVK LPSGIKLDVE KKDQIPEELL KKSTTSWSTA   200
SVRPSTLDIE PIAVKEFTEI PHAGKSYNPN NKAWSELINK EYKEEKARED   250
ERIALEKYKE RIRHLMETLD DNEEEESSSN EEEEEEEEEN ENENESTQCS   300
GSDKEIKLSI NKPVKNKKKT KYQRNKAKRH EEKVKLQQEL KELRQRVKDL   350
EEVINSEETE ILSAIESDSN KVKKSKKNKK HKLGTKYSVI DERLEIKFSD   400
ELSDSLRKLK PEGNLLYDTV RKLQSSGKVE TRVPVRKGRK YKQKITEKWT   450
HKDFK                                                    455