SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Systematic nameYOR112W
DescriptionUncharacterized protein YOR112W

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI    RPN10 Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionQ12453
SGD YOR112W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0000049tRNA bindingIDA:SGD.
Biological processGO:0006409tRNA export from nucleusIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
688Phosphoserine.
754Phosphoserine.

Sequence Information
Sequence length761
Molecular weight84769

	---------+----------+----------+----------+----------+
MNFSSIFKSI SNFQFPYTIE ETAITETALW QCFDGTRKAD SLPVTVFKAK   50
RSPENESLIL NAVHKSKILK IPGLCTVLET FDSDPQSTFI VTERVVPFPW   100
DNLGSLSQNK FGVELGISQL LATLGFLKNF VLGTLSKDSV FINIKGEWVL   150
FGLELCSSKE GLSAFEFASR ARSYYNIIGS QLPCEDPNTI DSMGLGLLIK   200
SLMAPSCLPK DWIVNVNMIS DGKITIENFR KRLENTETWR SNPLINFYQE   250
LRELHIKDPQ GKLVVMSNLE NLYLESREIF RNLTPGMIEN FIIPELCEII   300
KLLMTQSISS AASPIGMNFN ASHKLVPFLA IVLDLTSETN TFPVGFNDLI   350
TQSFKLPDRQ VRFLLLIYLP KLIGPLSKSE ISSRIYPHFI QGLTDSDATL   400
RLQTLKTIPC IVSCLTERQL NNELLRFLAK TQVDSDVEIR TWTVIIISKI   450
STILSTSVGN RSNILATAFT KSLKDPQVKP RLAALYGLEK SIELFDVNTI   500
ANKILTVIAP GLLDKSPIVR GRAKILFEEY LEKLEKEAQL IQTNDSTADS   550
EDVKDIDFEN YGCDEEDMNK EDNLLAAQFL NNLRLNSPSA TTPSNITESE   600
IDSAQDGSGW DDLSDTDGFI TNGTTESFDE TTNPVTTAST PKLFGKPIKI   650
NKSWNDELND DGWIQDESGP SKVPQKHTRP QNSTLAKSIA PSSRLSIKKK   700
KTTILAPRNI ASNSTVTTKS SLSNKTARSK PISSIRGSVT KKGNVDGWDD   750
DGDSDSWDTN W                                             761