SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Systematic nameYNL274C
DescriptionPutative 2-hydroxyacid dehydrogenase YNL274C

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionP53839
SGD YNL274C
Gene Ontology (GO)
Cellular componentGO:0005739mitochondrionIDA:SGD.
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:0047964glyoxylate reductase activityIMP:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0009436glyoxylate catabolic processIMP:SGD.
EC number 1.-.-.-

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length350
Molecular weight38831

	---------+----------+----------+----------+----------+
MSKKPIVLKL GKDAFGDQAW GELEKIADVI TIPESTTREQ FLREVKDPQN   50
KLSQVQVITR TARSVKNTGR FDEELALALP SSVVAVCHTG AGYDQIDVEP   100
FKKRHIQVAN VPDLVSNATA DTHVFLLLGA LRNFGIGNRR LIEGNWPEAG   150
PACGSPFGYD PEGKTVGILG LGRIGRCILE RLKPFGFENF IYHNRHQLPS   200
EEEHGCEYVG FEEFLKRSDI VSVNVPLNHN THHLINAETI EKMKDGVVIV   250
NTARGAVIDE QAMTDALRSG KIRSAGLDVF EYEPKISKEL LSMSQVLGLP   300
HMGTHSVETR KKMEELVVEN AKNVILTGKV LTIVPELQNE DWPNESKPLV   350