SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Systematic nameYLR049C
DescriptionUncharacterized protein YLR049C

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ12110
SGD YLR049C
Gene Ontology (GO)
Molecular functionGO:0005515protein bindingIPI:IntAct.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
127Phosphoserine.

Sequence Information
Sequence length428
Molecular weight49493

	---------+----------+----------+----------+----------+
MVNNIMHEYV PPSQRLFHSR HRITRNDLKE EALHSGTTDW TTILDTTIDK   50
DTNLISYAVP IIDNFAIPRA NSQGSPVAPS PNHRSTMYSS SSSSASSVFS   100
DGLFTPNNNR NSSGSSSLVI RPQKNLSVDS LIQENKRKIN SEKESLSLIA   150
NNNDETLCTH TDPSIQNLIK SETKRNILNL KFQNRNLFRR ELKLEKFWSN   200
LRSCHTSGDE TDLLLVISKH NLYWFGIPND FRLPIYKRCL YHYSELDEAG   250
FFSQYANNSL YLAIRKCCNN EEQETLSRSI FINLTKNVTW LNSRFDDNKD   300
NKNSYTVTEG KFYQDFPNLY YHLKDKLKLN VIMDFIKPVI RNFMTNALNK   350
HKLDGIGLEL LDILIVTTYY GPNKINAFLM DTFILNLLKQ CHYKFFVSNI   400
SELVIQISKI DCDLVILLED LRSRIDLD                           428