SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameYLH47
Systematic nameYPR125W
AliasMRS7
DescriptionLETM1 domain-containing protein YLH47, mitochondrial

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   HECTNARSP5   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
Methodprotein microarray (in vitro)
Reference"Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast."
Gupta R, Kus B, Fladd C, Wasmuth J, Tonikian R, Sidhu S, Krogan NJ, Parkinson J, Rotin D.
Mol Syst Biol. 3:116 (2007) [17551511]

Cross References
Swiss-Prot accessionQ06493
SGD YPR125W
Gene Ontology (GO)
Cellular componentGO:0005743mitochondrial inner membraneIDA:SGD.
Biological processGO:0051204protein insertion into mitochondrial membraneIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length454
Molecular weight52174

	---------+----------+----------+----------+----------+
MLKYRSLPIK RAIHHPAPGI TPISPRIMVS RLRVIPSFNL KFNRWNSSVP   50
ESSKKELKTT DGNQESASKV SPVKEKEKVP FKVKMQKALR HYWDGSKLLG   100
LEIKISSKLL MKSAAGYPLT RRENLQLKRT TQDIVRLVPF AAFLIIPFAE   150
LLLPFALKLF PNLLPSTYES SKKRENKLEN LRNTRKLMSE IIKNNKSHFK   200
PNNISEEQKA LFNRFYTHVR ATGVPESRQQ LIEVARLFTD DTVLDNVTRP   250
YLIALAKYMN LQPFGTDVML RYRIRYKMLE LKKDDLSIYY EDAEQLSLSE   300
LKTACASRGI RSVDVEPSVL YSNLRLWLNM RLKDKIPSTL LIMATAYNYG   350
NVQSKESLYD ALCDVLIGIP DELYHEVKVN VVKEDEASAK QKLKQLREQE   400
EIMKEEEQQE ENAIVSVKDE LSLDDQDKNI DAAAPDVKPH DTKPIGEAAA   450
IKEK                                                     454