SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Systematic nameYIL137C
DescriptionPutative zinc aminopeptidase YIL137C

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP40462
SGD YIL137C
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
EC number 3.4.11.-

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length946
Molecular weight107723

	---------+----------+----------+----------+----------+
MSDNLLSLEN PVVPSHYELR LEIDPKQSSP NFKGSAIIHL KFNPNSTTLA   50
SIEDSFTQFK LHSKDLIVLS AHATIGSTKF DLKISQDTGK HLSIFNSESP   100
IQLSNDCPLI LSVQYVGKIR DIKTHHDKTF GIFKTNFMDR KTGTANNHVV   150
ATHCQPFSAS NIFPCIDEPS NKSTFQLNIA TDAQYKAVSN TPVEMVEALD   200
SSQKHLVKFA KTPLMTTSVF GFSIGDLEFL KTEIKLEGDR TIPVSIYAPW   250
DIANAAFTLD TVQKYLPLLE SYFKCPYPLP KLDFVLLPYL SDMAMENFGM   300
ITIQLNHLLI PPNALANETV REQAQQLIVH ELVHQWMGNY ISFDSWESLW   350
FNESFATWLA CHILEQNGDL SHYWTSEPYL LQQVEPTMCR DAADVNGRSI   400
FQIAQRNTGI DSQTSDIFDP EAYTKGIIML RSLQLATGES HLQKGLESVF   450
EDTKTFHARS VKPMDIWNHI GKFLKSQNIT NFVSSWTRTP GLPVVKVEVE   500
EKDGKTQTKL TQHRFINQLS TEEKDQLEDV PYQVPLFGVL PDGKMDTKNV   550
LLTDRTLKFD YPILVINHLA QGYYRVSYES EECYALINDK ITEETLSEID   600
LRKIFLDLSQ FIGDEGFQNS IHLHGLFKIL NHIASPSTKI ASKYWDPLSK   650
GLEVLQTIDR ASLTSSKLQS FLKKKIVIPL FNKIDWPHGE FDKSTNPHEL   700
KVMSQVLFLN KNSAKCAELC QIYFKHLLQG PRSSVPLELV NSILVVVSQH   750
CANIKQWKKI FDLVKRSSCT GITNHVINMY DQNSSETAML IQNGAIESLG   800
FCLDSDIVKK TLNFITSNIE SEGMELALFG FNYNFKKRLN KNEKPQDQVV   850
RETIWEWYMG NFDQWARKAT RKGTTTGDHL HKALRSISLI IFQMFVADEP   900
QKIEKFINLE KEKLGQSLLS LDDIWASVQQ DEESRKTIRR DLASLV       946