SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard nameYHM1
Systematic nameYDL198C
AliasSHM1
DescriptionPutative mitochondrial carrier protein YHM1/SHM1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP38988
SGD YDL198C
Gene Ontology (GO)
Cellular componentGO:0005739mitochondrionIDA:SGD.
Molecular functionGO:0001409guanine nucleotide transporter activityIDA:SGD.
Biological processGO:0001408guanine nucleotide transportIDA:SGD.
Biological processGO:0006879iron ion homeostasisIMP:SGD.
Biological processGO:0000002mitochondrial genome maintenanceIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length300
Molecular weight33215

	---------+----------+----------+----------+----------+
MPHTDKKQSG LARLLGSASA GIMEIAVFHP VDTISKRLMS NHTKITSGQE   50
LNRVIFRDHF SEPLGKRLFT LFPGLGYAAS YKVLQRVYKY GGQPFANEFL   100
NKHYKKDFDN LFGEKTGKAM RSAAAGSLIG IGEIVLLPLD VLKIKRQTNP   150
ESFKGRGFIK ILRDEGLFNL YRGWGWTAAR NAPGSFALFG GNAFAKEYIL   200
GLKDYSQATW SQNFISSIVG ACSSLIVSAP LDVIKTRIQN RNFDNPESGL   250
RIVKNTLKNE GVTAFFKGLT PKLLTTGPKL VFSFALAQSL IPRFDNLLSK   300