SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Systematic nameYER130C
DescriptionZinc finger protein YER130C

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI    RPN10 Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP39959
SGD YER130C
Gene Ontology (GO)
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length443
Molecular weight50320

	---------+----------+----------+----------+----------+
MSLYPLQRFE SNDTVFSYTL NSKTELFNES RNNDKQHFTL QLIPNANANA   50
KEIDNNNVEI INDLTGNTIV DNCVTTATSS NQLERRLSIS DYRTENGNYY   100
EYEFFGRREL NEPLFNNDIV ENDDDIDLNN ESDVLMVSDD ELEVNERFSF   150
LKQQPLDGLN RISSTNNLKN LEIHEFIIDP TENIDDELED SFTTVPQSKK   200
KVRDYFKLNI FGSSSSSNNN SNSLGCEPIQ TENSSSQKMF KNRFFRSRKS   250
TLIKSLPLEQ ENEVLINSGF DVSSNEESDE SDHAIINPLK LVGNNKDIST   300
QSIAKTTNPF KSGSDFKMIE PVSKFSNDSR KDLLAAISEP SSSPSPSAPS   350
PSVQSSSSSH GLVVRKKTGS MQKTRGRKPS LIPDASKQFG CEFCDRRFKR   400
QEHLKRHVRS LHMCEKPFTC HICNKNFSRS DNLNQHVKTH ASL          443