SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameVAP1
Systematic nameYBR069C
AliasTAP1, TAT1
DescriptionValine/tyrosine/tryptophan amino-acid permease

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1K39        
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS
Reference"A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery."
Hitchcock AL, Auld K, Gygi SP, Silver PA.
Proc Natl Acad Sci U S A. 100(22):12735-40 (2003) [14557538]

Cross References
Swiss-Prot accessionP38085
SGD YBR069C
Gene Ontology (GO)
Molecular functionGO:0015171amino acid transporter activityIDA:SGD.
Biological processGO:0006865amino acid transportIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
1N-acetylmethionine.
4Phosphoserine.
13Phosphoserine.
18Phosphoserine.
20Phosphoserine.
44Phosphoserine.
80Phosphoserine.
84Phosphoserine.
596Phosphoserine.
599Phosphoserine.

Sequence Information
Sequence length619
Molecular weight68758

	---------+----------+----------+----------+----------+
MDDSVSFIAK EASPAQYSHS LHERTHSEKQ KRDFTITEKQ DEVSGQTAEP   50
RRTDSKSILQ RKCKEFFDSF KRQLPPDRNS ELESQEKNNL TKSIKSRHLV   100
MISLGTGIGT GLLVGNGQVL GTAGPAGLVL GYGIASIMLY CIIQAAGELG   150
LCYAGLTGNY TRYPSILVDP SLGFAVSVVY TIQWLTVLPL QLVTAAMTVK   200
YWTSVNADIF VAVVFVFVII INLFGSRGYA EAEFIFNSCK ILMVIGFVIL   250
AIIINCGGAG DRRYIGAEYW HNPGPFAHGF KGVCTVFCYA AFSYGGIEVL   300
LLSAAEQENP TKSIPNACKK VVYRILLIYM LTTILVCFLV PYNSDELLGS   350
SDSSGSHASP FVIAVASHGV KVVPHFINAV ILISVISVAN SSLYSGPRLL   400
LSLAEQGVLP KCLAYVDRNG RPLLCFFVSL VFGCIGFVAT SDAEEQVFTW   450
LLAISSLSQL FIWMSMSLSH IRFRDAMAKQ GRSMNEVGYK AQTGYWGSWL   500
AVLIAIFFLV CQFWVAIAPV NEHGKLNVKV FFQNYLAMPI VLFAYFGHKI   550
YFKSWSFWIP AEKIDLDSHR NIFVSPSLTE IDKVDDNDDL KEYENSESSE   600
NPNSSRSRKF FKRMTNFWC                                     619

	* Ubiquitinated lysine is denoted as red color.