SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameUBX6
Systematic nameYJL048C
DescriptionUBX domain-containing protein 6

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP47049
SGD YJL048C
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0030435sporulationIMP:SGD.
Biological processGO:0006511ubiquitin-dependent protein catabolic processIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length396
Molecular weight45016

	---------+----------+----------+----------+----------+
MYEMSGIDSL FHDRVVHDYS HTSEQVIVVY ISSAAGDNSW LHQWFKPGNL   50
SDEERENILW VRLVNGTKEC LLFKSIFPSS SAPSINILQN GLLECSIQGN   100
SLSREQDPWE TFINGLQSVF KGQVTKRKLF SKSNEEYQRV KRMIQNDKLE   150
RKYVFQNTND PQRKPQKWKQ LTVTDNVSYK SQKGFLAQNY CTLQLKLPNG   200
YTISNTFPPQ TKLHKVRMWL DYNCYDDGTP YLFHRNIPRV TLTRNDELKS   250
LQELDLLPRS TLILEPLEAN NKTFDYMEQS SLLHKVYSGL TSFWAKEPEV   300
DASSSRLGYQ RLGTNVSNSA NYSLQKLSSL DMVSDGGGGG GGDSMTPSAY   350
TTPRMYPSNG TSQLRQNVSE LNLSSNNSAS NTKVRTLGYS NNNGNN       396