SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameUBC7
Systematic nameYMR022W
AliasQRI8
DescriptionUbiquitin-conjugating enzyme E2-18 kDa

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   HECTNAUFD4   
* Blank: not determined, NA: not applicable.

References
[1]Evidence 
Method 
Reference"Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue."
Ravid T, Hochstrasser M.
Nat Cell Biol. 9(4):422-7 (2007) [17310239]

Cross References
Swiss-Prot accessionQ02159
SGD YMR022W
Gene Ontology (GO)
Cellular componentGO:0005783endoplasmic reticulumTAS:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0004842ubiquitin-protein ligase activityIDA:SGD.
Biological processGO:0006333chromatin assembly or disassemblyIMP:SGD.
Biological processGO:0030433ER-associated protein catabolic processIDA:SGD.
EC number 6.3.2.19

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length165
Molecular weight18520

	---------+----------+----------+----------+----------+
MSKTAQKRLL KELQQLIKDS PPGIVAGPKS ENNIFIWDCL IQGPPDTPYA   50
DGVFNAKLEF PKDYPLSPPK LTFTPSILHP NIYPNGEVCI SILHSPGDDP   100
NMYELAEERW SPVQSVEKIL LSVMSMLSEP NIESGANIDA CILWRDNRPE   150
FERQVKLSIL KSLGF                                         165