SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameTTP1
Systematic nameYBR015C
AliasMNN2
DescriptionProtein TTP1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP38069
SGD YBR015C
Gene Ontology (GO)
Cellular componentGO:0005794Golgi apparatusIDA:SGD.
Molecular functionGO:0000026alpha-1,2-mannosyltransferase activityIMP:SGD.
Biological processGO:0006486protein amino acid glycosylationIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length597
Molecular weight67774

	---------+----------+----------+----------+----------+
MLLTKRFSKL FKLTFIVLIL CGLFVITNKY MDENTSVKEY KEYLDRYVQS   50
YSNKYSSSSD AASADDSTPL RDNDEAGNEK LKSFYNNVFN FLMVDSPKGS   100
TAKQYNEACL LKGDIGDRPD HYKDLYKLSA KELSKCLELS PDEVASLTKS   150
HKDYVEHIAT LVSPKGTYKG SGIATVGGGK FSLMAFLIIK TLRNMGTTLP   200
VEVLIPPGDE GETEFCNKIL PKYNSKCIYV SDILPRETIE KFVFKGYQFK   250
SLALIASSFE NLLLLDADNF PIKPLDNIFN EEPYVSTGLV MWPDFWRRTT   300
HPLYYDIAGI AVDKKKRVRN SRDDITPPAV YTKDLKDLSD VPLSDLDGTI   350
PDVSTESGQL MINKTKHLAT ALLSLFYNVN GPTWYYPIFS QKAAGEGDKE   400
TFIAAANFYG LSFYQVRTRT GVEGYHDEDG FHGVAMLQHD FVQDYGRYLN   450
AMESIGNKYG GTKSADAIKF DKNYSLEKYT EEFFDNEDLN AKNHVDVMFI   500
HSNFPKFDPY DLSKSNFLTT NGKPARSYTA LKKVKNYDIE LENFKVLNEY   550
VCVNKNPFKY LDDLLGQDKT EWKRVCGYIT DRLAFLESTH DKAIAGK      597