SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard nameTMA46
Systematic nameYOR091W
AliasDFRP1
DescriptionTranslation machinery-associated protein 46

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI       
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionQ12000
SGD YOR091W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length345
Molecular weight39514

	---------+----------+----------+----------+----------+
MPPKKGKQAQ AAGKKKDNVD KTFGMKNKNR STKVQKYIKQ VQSQSDPKKE   50
EMRLKKLEEK KRREAEEAER RALFNPVADQ RVRAGVDPKS MVCALFKLGN   100
CNKGAKCKFS HDLNVGRRME KKDLYQDTRS EKENDTMDNW DEEKLRKVIL   150
SKHGNPKTTT DKVCKYFIEA VENGKYGWFW ICPNGGDKCM YRHSLPEGFV   200
LKTNEQKRLE RESLEKQPKI TLEEFIETER GKLDKSKLTP ITIANFAQWK   250
KDHVIAKINA EKKLSSKRKP TGREIILKMS AENKSFETDN ADMPDDVTQG   300
SAWDLTEFTD ALKKADHQDD GGIKDYGDGS NPTFDIKKAN SATLA        345