SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameTMA22
Systematic nameYJR014W
AliasRBF22
DescriptionTranslation machinery-associated protein 22

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI    RPN10 Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionP47089
SGD YJR014W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length198
Molecular weight22495

	---------+----------+----------+----------+----------+
MLREVIYCGI CSYPPEYCEF SGKLKRCKVW LSENHADLYA KLYGTDDNTQ   50
EVEAVTNKLA ESSIGEAREE KLEKDLLKIQ KKQENREQRE LAKKLSSKVI   100
IKREARTKRK FIVAISGLEV FDIDMKKLAK TFASRFATGC SVSKNAEKKE   150
EVVIQGDVMD EVETYIHSLL EEKGLKDVKV ETIDAKKKKK PAAEGAAK     198