SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameTLG1
Systematic nameYDR468C
DescriptionT-SNARE affecting a late Golgi compartment protein 1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   RINGSPRFTUL1   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceHigh MW Product Confirmation
MethodWestern blot
Reference"Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation."
Valdez-Taubas J, Pelham H.
EMBO J. 24(14):2524-32 (2005) [15973437]

Cross References
Swiss-Prot accessionQ03322
SGD YDR468C
Gene Ontology (GO)
Cellular componentGO:0005769early endosomeTAS:SGD.
Cellular componentGO:0000138Golgi trans cisternaTAS:SGD.
Cellular componentGO:0005802trans-Golgi networkTAS:SGD.
Molecular functionGO:0005486t-SNARE activityIDA:SGD.
Molecular functionGO:0005485v-SNARE activityTAS:SGD.
Biological processGO:0006906vesicle fusionTAS:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
31Phosphothreonine.

Sequence Information
Sequence length224
Molecular weight25817

	---------+----------+----------+----------+----------+
MNNSEDPFQQ VVKDTKEQLN RINNYITRHN TAGDDDQEEE IQDILKDVEE   50
TIVDLDRSII VMKRDENEDV SGREAQVKNI KQQLDALKLR FDRRIQESTQ   100
TTIPLEETVE NSTLNTSMAE NNDGGMSNPF QEQMLREQDV HLDGIHKTMQ   150
NLHIQAQTMG DELENQGQLL DNMDEGMDGV VNKLARGRRQ LEWVYEKNKE   200
KYDDCCIGLL IVVLIVLLVL AFIA                               224