SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameTEC1
Systematic nameYBR083W
AliasROC1
DescriptionTy transcription activator TEC1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1  CDC34RINGSCFCDC4   
2  CDC34RINGSCFDIA2   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast."
Chou S, Huang L, Liu H.
Cell. 119(7):981-90 (2004) [15620356]
[2]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast."
Bao MZ, Schwartz MA, Cantin GT, Yates JR 3rd, Madhani HD.
Cell. 119(7):991-1000 (2004) [15620357]

Cross References
Swiss-Prot accessionP18412
SGD YBR083W
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIC:SGD.
Molecular functionGO:0003704specific RNA polymerase II transcription fa...IDA:SGD.
Biological processGO:0001403invasive growth (sensu Saccharomyces)TAS:SGD.
Biological processGO:0045944positive regulation of transcription from R...IDA:SGD.
Biological processGO:0007124pseudohyphal growthIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
86Phosphoserine.
325Phosphoserine.

Sequence Information
Sequence length486
Molecular weight55157

	---------+----------+----------+----------+----------+
MSLKEDDFGK DNSRNIESYT GRIFDVYIQK DSYSQSALDD MFPEAVVSTA   50
ACVKNEAEDN INLIDTHPQF ELVNTGLGAK SDDLKSPSAK ATFTDKQRKN   100
EVPNISVSNY FPGQSSETSS TTESWTIGCD KWSEKVEEAF LEALRLIMKN   150
GTTKIKIRNA NFGRNELISL YIKHKTNEFR TKKQISSHIQ VWKKTIQNKI   200
KDSLTLSSKE KELLHLIEHG AEQTTENSNL FYDIFEEIID SLPSVSDSGS   250
LTPKNLYVSN NSSGLSVHSK LLTPITASNE KKIENFIKTN AASQAKTPLI   300
YAKHIYENID GYKCVPSKRP LEQLSPTELH QGDRPNKASF SNKKAILESA   350
KKIEIEQRKI INKYQRISRI QEHESNPEFS SNSNSGSEYE SEEEVVPRSA   400
TVTQLQSRPV PYYKNNGMPY SLSKVRGRPM YPRPAEDAYN ANYIQGLPQY   450
QTSYFSQLLL SSPQHYEHSP HQRNFTPSNQ SHGNFY                  486