SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard nameTDH1
Systematic nameYJL052W
AliasGPD1, SSS2
DescriptionGlyceraldehyde-3-phosphate dehydrogenase 1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI       
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS
Reference"Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets."
Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.
Mol Cell Proteomics. 4(6):741-51 (2005) [15699485]

Cross References
Swiss-Prot accessionP00360
SGD YJL052W
Gene Ontology (GO)
Cellular componentGO:0009277chitin- and beta-glucan-containing cell wallIDA:SGD.
Cellular componentGO:0005811lipid particleIDA:SGD.
Cellular componentGO:0005739mitochondrionIDA:SGD.
Molecular functionGO:0004365glyceraldehyde-3-phosphate dehydrogenase (p...IDA:SGD.
Biological processGO:0006094gluconeogenesisIEP:SGD.
Biological processGO:0006096glycolysisIEP:SGD.
EC number 1.2.1.12

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
149Phosphoserine.
199Phosphothreonine.
201Phosphoserine.
207Phosphoserine.
208Phosphoserine.
291Phosphoserine.
310Phosphoserine.

Sequence Information
Sequence length332
Molecular weight35750

	---------+----------+----------+----------+----------+
MIRIAINGFG RIGRLVLRLA LQRKDIEVVA VNDPFISNDY AAYMVKYDST   50
HGRYKGTVSH DDKHIIIDGV KIATYQERDP ANLPWGSLKI DVAVDSTGVF   100
KELDTAQKHI DAGAKKVVIT APSSSAPMFV VGVNHTKYTP DKKIVSNASC   150
TTNCLAPLAK VINDAFGIEE GLMTTVHSMT ATQKTVDGPS HKDWRGGRTA   200
SGNIIPSSTG AAKAVGKVLP ELQGKLTGMA FRVPTVDVSV VDLTVKLEKE   250
ATYDQIKKAV KAAAEGPMKG VLGYTEDAVV SSDFLGDTHA SIFDASAGIQ   300
LSPKFVKLIS WYDNEYGYSA RVVDLIEYVA KA                      332