SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameSTE7
Systematic nameYDL159W
DescriptionSerine/threonine-protein kinase STE7

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1  CDC34RINGSCF    
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex."
Wang Y, Ge Q, Houston D, Thorner J, Errede B, Dohlman HG.
J Biol Chem. 278(25):22284-9 (2003) [12668671]

Cross References
Swiss-Prot accessionP06784
SGD YDL159W
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Cellular componentGO:0043332mating projection tipIDA:SGD.
Molecular functionGO:0004708MAP kinase kinase activityTAS:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0001403invasive growth (sensu Saccharomyces)IMP:SGD.
Biological processGO:0000750pheromone-dependent signal transduction dur...TAS:SGD.
Biological processGO:0007124pseudohyphal growthIMP:SGD.
EC number 2.7.12.2

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
359Phosphoserine.
363Phosphothreonine.

Sequence Information
Sequence length515
Molecular weight57709

	---------+----------+----------+----------+----------+
MFQRKTLQRR NLKGLNLNLH PDVGNNGQLQ EKTETHQGQS RIEGHVMSNI   50
NAIQNNSNLF LRRGIKKKLT LDAFGDDQAI SKPNTVVIQQ PQNEPVLVLS   100
SLSQSPCVSS SSSLSTPCII DAYSNNFGLS PSSTNSTPST IQGLSNIATP   150
VENEHSISLP PLEESLSPAA ADLKDTLSGT SNGNYIQLQD LVQLGKIGAG   200
NSGTVVKALH VPDSKIVAKK TIPVEQNNST IINQLVRELS IVKNVKPHEN   250
IITFYGAYYN QHINNEIIIL MEYSDCGSLD KILSVYKRFV QRGTVSSKKT   300
WFNELTISKI AYGVLNGLDH LYRQYKIIHR DIKPSNVLIN SKGQIKLCDF   350
GVSKKLINSI ADTFVGTSTY MSPERIQGNV YSIKGDVWSL GLMIIELVTG   400
EFPLGGHNDT PDGILDLLQR IVNEPSPRLP KDRIYSKEMT DFVNRCCIKN   450
ERERSSIHEL LHHDLIMKYV SPSKDDKFRH WCRKIKSKIK EDKRIKREAL   500
DRAKLEKKQS ERSTH                                         515