SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameSPT7
Systematic nameYBR081C
DescriptionTranscriptional activator SPT7

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   HECTNATOM1   
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes."
Saleh A, Collart M, Martens JA, Genereaux J, Allard S, Cote J, Brandl CJ.
J Mol Biol. 282(5):933-46 (1998) [9753545]

Cross References
Swiss-Prot accessionP35177
SGD YBR081C
Gene Ontology (GO)
Cellular componentGO:0005739mitochondrionIDA:SGD.
Cellular componentGO:0000124SAGA complexIDA:SGD.
Cellular componentGO:0046695SLIK (SAGA-like) complexIPI:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Molecular functionGO:0005198structural molecule activityIDA:SGD.
Biological processGO:0000747conjugation with cellular fusionIMP:SGD.
Biological processGO:0016573histone acetylationTAS:SGD.
Biological processGO:0006461protein complex assemblyIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
78Phosphothreonine, by ATM or ATR.
88Phosphoserine.

Sequence Information
Sequence length1332
Molecular weight152617

	---------+----------+----------+----------+----------+
MTERIPIKNY QRTNAKALLK LTEKLFNKNF FDLYLTSQQL VVLEYLLSIS   50
SEEDKLKAWD YFLKGNIALN VEKSFPLTQE EEHHGAVSPA VDTRSDDVSS   100
QTIKDNNNTN TNTSISNENH VENEIEDKGD NAIANEDNFV NNDESDNVEE   150
DLFKLDLEDL KQQISGTRFI GNLSLKIRYV LWQCAIDYIY CDRNEFGDEN   200
DTEYTLLDVE EKEEEEIGKN EKPQNKEGIS KFAEDEDYDD EDENYDEDST   250
DVKNVDDPPK NLDSISSSNI EIDDERRLVL NISISKETLS KLKTNNVEEI   300
MGNWNKIYHS FEYDKETMIK RLKLEESDKM IEKGKKKRSR SDLEAATDEQ   350
DRENTNDEPD TNQKLPTPEG STFSDTGNKR PKQSNLDLTV NLGIENLSLK   400
HLLSSIQQKK SQLGISDYEL KHLIMDVRKN RSKWTSDERI GQEELYEACE   450
KVVLELRNYT EHSTPFLNKV SKREAPNYHQ IIKKSMDLNT VLKKLKSFQY   500
DSKQEFVDDI MLIWKNCLTY NSDPSHFLRG HAIAMQKKSL QLIRMIPNIT   550
IRNRADLEKE IEDMEKDKDY ELDEEEEVAG SGRKGLNMGA HMLAKENGKV   600
SEKDSSKTVK DEAPTNDDKL TSVIPEGEKE KDKTASSTVT VHENVNKNEI   650
KENGKNEEQD MVEESSKTED SSKDADAAKK DTEDGLQDKT AENKEAGENN   700
EEEEDDDDED EDEDMVDSQS YLLEKDDDRD DLEISVWKTV TAKVRAEICL   750
KRTEYFKNGK LNSDSEAFLK NPQRMKRFDQ LFLEYKEQKA LESYRQKIEQ   800
NSIMKNGFGT VLKQEDDDQL QFHNDHSLNG NEAFEKQPND IELDDTRFLQ   850
EYDISNAIPD IVYEGVNTKT LDKMEDASVD RMLQNGINKQ SRFLANKDLG   900
LTPKMNQNIT LIQQIRHICH KISLIRMLQS PLSAQNSRSN PNAFLNNHIY   950
NYTIIDDSLD IDPVSQLPTH DYKNNRELIW KFMHKNISKV AMANGFETAH   1000
PSAINMLTEI AGDYLSNLIK TLKLHHETNS LNRGTNVEML QTTLLENGIN   1050
RPDDLFSYVE SEFGKKTKKL QDIKQKLESF LRALLRPTLQ ELSERNFEDE   1100
SQSFFTGDFA SELTGEDFFG FRELGLEKEF GVLSSSVPLQ LLTTQFQTVD   1150
GETKVQAKKI QPEESDSIVY KKITKGMLDA GSFWNTLLPL LQKDYERSKA   1200
YIAKQSKSSA NDKTSMTSTE DNSFALLEED QFVSKKTATK ARLPPTGKIS   1250
TTYKKKPIAS AFILPEEDLE NDVKADPTTT VNAKVGAEND GDSSLFLRTP   1300
QPLDPLDMDD AFDDTNMGSN SSFSLSLPRL NQ                      1332