SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameSMF1
Systematic nameYOL122C
AliasESP1
DescriptionManganese transporter SMF1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1   HECTNARSP5  Vacuolar Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidenceHigh MW Product Confirmation
MethodWestern blot
Reference"Transferrin receptor-like proteins control the degradation of a yeast metal transporter."
Stimpson HE, Lewis MJ, Pelham HR.
EMBO J. 25(4):662-72 (2006) [16456538]

Cross References
Swiss-Prot accessionP38925
SGD YOL122C
Gene Ontology (GO)
Cellular componentGO:0005886plasma membraneIDA:SGD.
Cellular componentGO:0000324vacuole, cell cycle-correlated morphologyIDA:SGD.
Molecular functionGO:0005384manganese ion transporter activityIMP:SGD.
Biological processGO:0006828manganese ion transportIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
24Phosphoserine.

Sequence Information
Sequence length575
Molecular weight63264

	---------+----------+----------+----------+----------+
MVNVGPSHAA VAVDASEARK RNISEEVFEL RDKKDSTVVI EGEAPVRTFT   50
SSSSNHERED TYVSKRQVMR DIFAKYLKFI GPGLMVSVAY IDPGNYSTAV   100
DAGASNQFSL LCIILLSNFI AIFLQCLCIK LGSVTGLDLS RACREYLPRW   150
LNWTLYFFAE CAVIATDIAE VIGTAIALNI LIKVPLPAGV AITVVDVFLI   200
MFTYKPGASS IRFIRIFECF VAVLVVGVCI CFAIELAYIP KSTSVKQVFR   250
GFVPSAQMFD HNGIYTAISI LGATVMPHSL FLGSALVQPR LLDYDVKHGN   300
YTVSEEQDKV KKSKSTEEIM EEKYFNYRPT NAAIKYCMKY SMVELSITLF   350
TLALFVNCAI LVVAGSTLYN SPEADGADLF TIHELLSRNL APAAGTIFML   400
ALLLSGQSAG VVCTMSGQIV SEGHINWKLQ PWQRRLATRC ISIIPCLVIS   450
ICIGREALSK ALNASQVVLS IVLPFLVAPL IFFTCKKSIM KTEITVDHTE   500
EDSHNHQNNN DRSAGSVIEQ DGSSGMEIEN GKDVKIVYMA NNWIITVIAI   550
IVWLFLSLLN VYAIVQLGMS HGDIS                              575