SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameSKS1
Systematic nameYPL026C
AliasSHA3
DescriptionSerine/threonine-protein kinase SKS1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ12505
SGD YPL026C
Gene Ontology (GO)
Cellular componentGO:0005737cytoplasmIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0015758glucose transportIGI:SGD.
Biological processGO:0045944positive regulation of transcription from R...IGI:SGD.
Biological processGO:0009749response to glucose stimulusIGI:SGD.
EC number 2.7.11.1

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length502
Molecular weight57844

	---------+----------+----------+----------+----------+
MLSDCLLNNF RITAQIGSGA YGLVFHVVDI LTSREYAVKT VFKSSSMDEF   50
YNKNGLNNNS QVARTTLLQT QLYHFFKSFQ KKLFLPSVDL DSILQLTENE   100
LNRLPHYREI AFQLRVQSHG NIVKIHQVLE SSIATFIVMD YYDRDLFTSI   150
VDDKHFVNHG ILIKKVFLQL CSALDHCHRL GIYHCDIKPE NVLLDRNDNA   200
YLCDFGLSTK SKYLAPNVCV GSSYYMAPER ILYCLNTTTN GIHVDECCSS   250
LPTDTGDIWS LGIILINLTC IRNPWLKAHQ KEDNTFQHFA NDNNVLKKIL   300
PISDELFTVL TKILQLNPYT RIDMKTLMSE VSSLTSFTRE GPLSQVPILS   350
SEVYMTHIIR NENLFLSDLS HFSADQEQQQ QQQQQQQQVQ EQEQEQKQEQ   400
IQNQEQAQQQ QEEEDAEPES DIPSTYNSDG SMEKYEYTNN HNNSTFLTSS   450
MDSTPYQSDI DDVSASKDCK FQQDTLRNRL LCLQMNFSTL TDGPNEKWLP   500
DY                                                       502