SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameSDA1
Systematic nameYGR245C
DescriptionProtein SDA1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP53313
SGD YGR245C
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIDA:SGD.
Biological processGO:0030036actin cytoskeleton organization and biogenesisIMP:SGD.
Biological processGO:0042255ribosome assemblyTAS:SGD.
Biological processGO:0007089traversing start control point of mitotic c...IMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
278Phosphoserine.

Sequence Information
Sequence length767
Molecular weight86618

	---------+----------+----------+----------+----------+
MGRRSRAAML PTNIILLQNL VKRDPESYQE EFLQQYAHYE SLRDIFMLNG   50
LAGGDSAAAT NGLDVGNGSS TMAGTNGTTM STSTSQLIEL VGFVSQVCSC   100
FPRETANFPS ELKQLLLEHH KSLPFELKEK ILSCLTMLRN KDVITAEELI   150
QSLFPLLVAY SSHGNSLGVN SHAKELRKII YTNLISLLKS CNTNGKNQKL   200
NKSTQAVCFN LLDQPDSQGI WATKLTRELW RRGIWDDSRT VEIMTQAALH   250
QDVKIVMSGV MFFLDADRER EENFEENSED EDGFDLDALR HKMQVNKKTG   300
RRGKKLENAI KTVKKKKKNG PGAPQGYLNF SAIHLLRDPQ GFAEKLFKEH   350
LSGKTKNKFD MEQKISLMQL LSRLIGTHKL IVLGIYTFFL KYLTPKQRDV   400
TRIMSACAQA CHDLVPPEVI NVMVRKIADE FVSDGVANEV AAAGINTIRE   450
ICSRAPLAID EILLQDLVEY KGSKAKGVNM AAKSLIALYR DVAPEMLKKK   500
DRGKNAAMEV QEAKKGGKDS KRPQFGADNS VQGIAGIELL AKWKKEHGEE   550
SENEDADANW EVDVDSEEDD VDGEWVTMDS DKEYDVDMED SDDEKDNAKG   600
KESDSDLELS DDDDEKEVKD EQEDADIDPE AAFREIASTR ILTPADFAKL   650
QELRNEESVA KIMGIHKQDK REELVDASTL TGPIKYKQSR EERLQKVLEG   700
REGRDKFGSR RGKRDNMRST TNREKERRKN FVMSIHKRSV RGKQKMSLRD   750
KQKVLRAHIT KQKKKGY                                       767