SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard nameSCS2
Systematic nameYER120W
DescriptionVesicle-associated membrane protein-associated protein SCS2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (HB-ubiquitin (a tandem affinity tag under denaturing conditions)), LC/MS
Reference"A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking."
Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P.
Mol Cell Proteomics. 5(4):737-48 (2006) [16432255]

Cross References
Swiss-Prot accessionP40075
SGD YER120W
Gene Ontology (GO)
Cellular componentGO:0005789endoplasmic reticulum membraneIDA:SGD.
Cellular componentGO:0016021integral to membraneIDA:SGD.
Cellular componentGO:0031965nuclear membraneIDA:SGD.
Molecular functionGO:0033149FFAT motif bindingIMP:SGD.
Biological processGO:0006348chromatin silencing at telomereIGI:SGD.
Biological processGO:0042992negative regulation of transcription factor...IMP:SGD.
Biological processGO:0008654phospholipid biosynthetic processIMP:SGD.
Biological processGO:0032377regulation of intracellular lipid transportIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
2N-acetylserine.
106Phosphoserine.
153Phosphoserine.

Sequence Information
Sequence length244
Molecular weight26926

	---------+----------+----------+----------+----------+
MSAVEISPDV LVYKSPLTEQ STEYASISNN SDQTIAFKVK TTAPKFYCVR   50
PNAAVVAPGE TIQVQVIFLG LTEEPAADFK CRDKFLVITL PSPYDLNGKA   100
VADVWSDLEA EFKQQAISKK IKVKYLISPD VHPAQNQNIQ ENKETVEPVV   150
QDSEPKEVPA VVNEKEVPAE PETQPPVQVK KEEVPPVVQK TVPHENEKQT   200
SNSTPAPQNQ IKEAATVPAE NESSSMGIFI LVALLILVLG WFYR         244