SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameRTN1
Systematic nameYDR233C
DescriptionReticulon-like protein 1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ04947
SGD YDR233C
Gene Ontology (GO)
Cellular componentGO:0005789endoplasmic reticulum membraneIDA:SGD.
Cellular componentGO:0005794Golgi apparatusIDA:SGD.
Cellular componentGO:0005739mitochondrionIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
186Phosphothreonine.
219Phosphothreonine.

Sequence Information
Sequence length295
Molecular weight32916

	---------+----------+----------+----------+----------+
MSASAQHSQA QQQQQQKSCN CDLLLWRNPV QTGKYFGGSL LALLILKKVN   50
LITFFLKVAY TILFTTGSIE FVSKLFLGQG LITKYGPKEC PNIAGFIKPH   100
IDEALKQLPV FQAHIRKTVF AQVPKHTFKT AVALFLLHKF FSWFSIWTIV   150
FVADIFTFTL PVIYHSYKHE IDATVAQGVE ISKQKTQEFS QMACEKTKPY   200
LDKVESKLGP ISNLVKSKTA PVSSTAGPQT ASTSKLAADV PLEPESKAYT   250
SSAQVMPEVP QHEPSTTQEF NVDELSNELK KSTKNLQNEL EKNNA        295