SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameRSB1
Systematic nameYOR049C
DescriptionSphingoid long-chain base transporter RSB1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ08417
SGD YOR049C
Gene Ontology (GO)
Cellular componentGO:0005783endoplasmic reticulumIDA:SGD.
Cellular componentGO:0016021integral to membraneIDA:SGD.
Cellular componentGO:0005886plasma membraneIDA:SGD.
Molecular functionGO:0004012phospholipid-translocating ATPase activityIDA:SGD.
Biological processGO:0015908fatty acid transportIDA:SGD.
Biological processGO:0045332phospholipid translocationIMP:SGD.
Biological processGO:0009636response to toxinIEP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length382
Molecular weight43256

	---------+----------+----------+----------+----------+
MSNATNNTLG SLLPQLEAAA NRNSLYGGMV PNLRFNITMI VIWGILLTIH   50
VVQLLMRQYW FSIAFICTGI LEVLGFIGRT WSHSNVADMD AFLLNMICLT   100
IAPVFTMGGI YYQLAKLIEV YGHRFSLLPS PMAYSFIFIC SDIVSLVVQA   150
VGGGLCGVAV TDGTSTTTGN HVFIAGLAIQ VASMAIFLML WFHFLFRIYI   200
SVRWEHINSR PISLSLLKIS QTEVDYLYRE KFHFLRLEPK RWVFHYFNLA   250
ITVAVLTIFT RCCYRLAELV VGWDGYLITH EWYFIILDAL MMAIATVTLT   300
IFHPGFAFKG RSTSIPITPG HVDPETLPHT DDVEDILDTS DSKQFDIEKE   350
EFQASMKYPI STFKQFMSKI ANLFSSKKKA KL                      382