SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameRME1
Systematic nameYGR044C
DescriptionZinc finger protein RME1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP32338
SGD YGR044C
Gene Ontology (GO)
Cellular componentGO:0005634nucleusIDA:SGD.
Molecular functionGO:0016566specific transcriptional repressor activityIDA:SGD.
Biological processGO:0007126meiosisTAS:SGD.
Biological processGO:0000122negative regulation of transcription from R...IDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length300
Molecular weight33904

	---------+----------+----------+----------+----------+
MSPCYGQNSA IAKGSWNREV LQEVQPIYHW HDFGQNMKEY SASPLEGDSS   50
LPSSLPSSTE DCLLLSLENT ITVIAGNQRQ AYDSTSSTEE GTAPQLRPDE   100
IADSTHCITS LVDPEFRDLI NYGRQKGANP VFIESNTTEQ SHSQCILGYP   150
QKSHVAQLYH DPKVLSTISE GQTKRGSYHC SHCSEKFATL VEFAAHLDEF   200
NLERPCKCPI EQCPWKILGF QQATGLRRHC ASQHIGELDI EMEKSLNLKV   250
EKYPGLNCPF PICQKTFRRK DAYKRHVAMV HNNADSRFNK RLKKILNNTK   300