SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameRAX2
Systematic nameYLR084C
DescriptionBud site selection protein RAX2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ12465
SGD YLR084C
Gene Ontology (GO)
Cellular componentGO:0005935cellular bud neckIDA:SGD.
Cellular componentGO:0005621cellular bud scarIDA:SGD.
Cellular componentGO:0005739mitochondrionIDA:SGD.
Biological processGO:0000282cellular bud site selectionIGI:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length1220
Molecular weight133959

	---------+----------+----------+----------+----------+
MFVHRLWTLA FPFLVEISKA SQLENIKSLL DIEDNVLPNL NISQNNSNAV   50
QILGGVDALS FYEYTGQQNF TKEIGPETSS HGLVYYSNNT YIQLEDASDD   100
TRIDKITPFG VDSFILSGSG TINNISVGNQ ILYNLSTLSM TPIFNQSLGA   150
VQAVLADNSS IYFGGNFSYN NGSMTGYSAL IWDSISNTTQ LLPFGGFGEN   200
SSVNSIVKLN NDNILFAGQF YTLDDPSALI SSSNNGTNST SSLNATTLEL   250
GQRIPLRYAS WDSQGSTTFA SDSLVCPNTN EDAWLYPDTS GSLVCNLPYE   300
VSPTKIRLYN SQRSDSEISV FQILTDPSSS IMNLTYLDPL SGELKNCGEF   350
CPLYSRATLL SASQNVSSSM DMITFIDNNK TDVKWTSDFQ DFAFVNELPV   400
SSLKFVALNS YGGSVGLSGL ELYQDTFSTY ANDSLNEYGC SALTNDSSSS   450
TLSSNDWYNG LTGESYIAAK YVPDQNEPIP RVKFYPNIIH PGHYTINMYT   500
PGCLQDNTCS ARGIVNVTMW NQQNNTIMKT YLIYQNNDNL KYDQIYSGYL   550
DFSPEIVLEY VSGIYTTNTA TVVVADQVNV ITVSLDAFNT LSDSSNAKKE   600
TLLNGILQYQ KSNFTSTRLN ETKVGNTTLN LFPVKNYPKN SSLYADIYDN   650
KLVIGGVSNR ISIVDLNDDF EVTSSKNQTI QGDVHGITKT NQGLLIFGDI   700
LSSNNQSAVF LFNGSFENVF NQSRTVNSAL NISLANNDFI VLDNDYVVNA   750
SSNALIRNSS SFSLSLWAAG NNGDGDVLFS GAVSHMQYGN LNGSVRFLNE   800
NEIEPLNLEG GIVPYLGAYL NESATAYAYE VDSLNKIYFS NEVYPSWNWS   850
SGITQMLYAD NQTLLAVSAG SSTTAELSIF DLRNLTMIAN ETLGSNARIN   900
ALVNFEKNCS MLVGGDFQMT EPNCTGLCLY NYESKTWSTF LNNTIFGEIT   950
QLSFTNSSEL IISGLFETKE YQSIRLGSFN LTNSTMIPLL SGSEGKLNSF   1000
TVTEDSIVAW NDTSLFIYRN QEWNITSLPG NASSISSVSA IYTDIESNTL   1050
NKRGINNVNN GSILLLNGNF NISQYGYLQS LLFDFQKWTP YFISETTNTS   1100
NYNPIIFINR DVSTEFNSQS PLANVNITVT SPQSTSSQPP SSSASSESKS   1150
KSKKKKIGRG FVVLIGLALA LGTVSVLGIA GVILAYVFKD PEGDYKPIKP   1200
RIDENEMLDT VPPEKLMKFV                                     1220