SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard namePSD1
Systematic nameYNL169C
DescriptionPhosphatidylserine decarboxylase 1 alpha chain

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP39006
SGD YNL169C
Gene Ontology (GO)
Cellular componentGO:0005743mitochondrial inner membraneTAS:SGD.
Molecular functionGO:0004609phosphatidylserine decarboxylase activityTAS:SGD.
Biological processGO:0006656phosphatidylcholine biosynthetic processIDA:SGD.
EC number 4.1.1.65

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
463Pyruvic acid (Ser) (By similarity).

Sequence Information
Sequence length500
Molecular weight56595

	---------+----------+----------+----------+----------+
MSIMPVKNAL AQGRTLLMGR MPAVKFSTRM QLRNRTAVLW NRKFSTRLFV   50
QQRRSSGEIV DRAKAAAANS GRKQVSMKWV VLTSFTIVLG TILLVSRNDS   100
TEEDATEGKK GRRTRKIKIF NNNWLFFCYS TLPLNAMSRL WGQVNSLTLP   150
IWVRPWGYRL YSFLFGVNLD EMEDPDLTHY ANLSEFFYRN IKPGTRPVAQ   200
GEDVIASPSD GKILQVGIIN SETGEIEQVK GMTYSIKEFL GTHSHPLMSK   250
SASSLDLTSD EEKHREFARV NRIQLAGSED TEQPLLNFKN EGDQSVREFK   300
PSVSKNIHLL SQLSLNYFSN GFSCSEPHDT ELFFAVIYLA PGDYHHFHSP   350
VDWVCKVRRH FPGDLFSVAP YFQRNFPNLF VLNERVALLG SWKYGFFSMT   400
PVGATNVGSI KLNFDQEFVT NSKSDKHLEP HTCYQAVYEN ASKILGGMPL   450
VKGEEMGGFE LGSTVVLCFE APTEFKFDVR VGDKVKMGQK LGIIGKNDLK   500