SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard namePOP1
Systematic nameYNL221C
DescriptionRibonucleases P/MRP protein subunit POP1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionP41812
SGD YNL221C
Gene Ontology (GO)
Cellular componentGO:0005655nucleolar ribonuclease P complexIDA:SGD.
Cellular componentGO:0000172ribonuclease MRP complexIDA:SGD.
Biological processGO:0006379mRNA cleavageIPI:SGD.
Biological processGO:0006364rRNA processingIPI:SGD.
Biological processGO:0008033tRNA processingTAS:SGD.
EC number 3.1.26.5

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length875
Molecular weight100395

	---------+----------+----------+----------+----------+
MSGSLSRGNG GKKVLNKNQL LKRNRIRNAR SIRAEAVAAS STKTGTPSDL   50
SESGSKLNVD QFISSRQFEV KQLQLAMHNS KAASSTRIFQ ALPRKLRRRT   100
ASHNVRRIPK RMRNRALREM RKSDQQDVLK GSSASSRKAH GLNAKQLYKA   150
RMSIKLLRLA SKSTSMKLSM PPEVTSSNCH VRQKIKTLKR MIKESSTANP   200
NIKLLNNRMG SYDCTGVNEL APIPKGRVKY TKRQKHFAWL PTHIWNAKRS   250
HMMKRWGYQM VWAPTQKCFK LTHRLGGDTC SSDGALCMDS SYIGTIIVKD   300
KSNDSEGDFL KSIIGKLTAE RANLRKYREG QVLFQGLIYS FNEENGEDST   350
KPLGPCDVFW VQKDTAIIRL HPSIYTQVFN ILLQHKEKLT VQDCRYSLAS   400
VTLKGAKALE SLASCLRSTE YSKSFEQFKM VSMITDHNAL PQRCTFAFEA   450
IDPRHLAAPK KLNDSQRKTV NSDDILSLHE NYPQDEINAV FNELCDPESR   500
TQSYNNQNTL KEISARRYKL LTATPNSINK TTVPFKESDD PSIPLVIIRR   550
LKTRDWIVVL PWFWLLPLWH LLNRIPRMYH IGLRQFQQIQ YENKQLYFPD   600
DYPFTQLGYI ENSFYKKEAS KTKWDRKPMG KRINFEKIKD IHNTKLPAYS   650
GEIGDFFSSD WRFLQILRNG IDYLQRNDKT LELMDSKKTG QFNAQGVRDI   700
NCVNDVLEFC KDYEAKTKAM SLSIEENIPV ALCKNRKCQF RTPDSISVNS   750
SSFSLTFFPR CIIAVSCTLL ERGHPKDNAR IYQVPEKDLE HWLQLAKGVY   800
RPNGRKDHDL KIPLPEVHDL IGFITSGTYH LNCGNGMGIG FIDHHAAIRQ   850
PTRYVLIRNV GTNTYRLGEW SKISV                              875