SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard namePGM1
Systematic nameYKL127W
DescriptionPhosphoglucomutase-1

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionP33401
SGD YKL127W
Gene Ontology (GO)
Molecular functionGO:0004614phosphoglucomutase activityIMP:SGD.
Biological processGO:0006008glucose 1-phosphate utilizationIMP:SGD.
Biological processGO:0006010glucose 6-phosphate utilizationIMP:SGD.
EC number 5.4.2.2

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
120Phosphoserine.

Sequence Information
Sequence length570
Molecular weight63112

	---------+----------+----------+----------+----------+
MSLLIDSVPT VAYKDQKPGT SGLRKKTKVF MDEPHYTENF IQATMQSIPN   50
GSEGTTLVVG GDGRFYNDVI MNKIAAVGAA NGVRKLVIGQ GGLLSTPAAS   100
HIIRTYEEKC TGGGIILTAS HNPGGPENDL GIKYNLPNGG PAPESVTNAI   150
WEASKKLTHY KIIKNFPKLN LNKLGKNQKY GPLLVDIIDP AKAYVQFLKE   200
IFDFDLIKSF LAKQRKDKGW KLLFDSLNGI TGPYGKAIFV DEFGLPAEEV   250
LQNWHPLPDF GGLHPDPNLT YARTLVDRVD REKIAFGAAS DGDGDRNMIY   300
GYGPAFVSPG DSVAIIAEYA PEIPYFAKQG IYGLARSFPT SSAIDRVAAK   350
KGLRCYEVPT GWKFFCALFD AKKLSICGEE SFGTGSNHIR EKDGLWAIIA   400
WLNILAIYHR RNPEKEASIK TIQDEFWNEY GRTFFTRYDY EHIECEQAEK   450
VVALLSEFVS RPNVCGSHFP ADESLTVIDC GDFSYRDLDG SISENQGLFV   500
KFSNGTKFVL RLSGTGSSGA TIRLYVEKYT DKKENYGQTA DVFLKPVINS   550
IVKFLRFKEI LGTDEPTVRT                                     570