SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard namePAP1
Systematic nameYKR002W
DescriptionPoly(A) polymerase

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1 MULTI       
* Blank: not determined, NA: not applicable.

References
[1]EvidenceUb-conjugate Confirmation
MethodWestern blot
Reference"Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle."
Mizrahi N, Moore C.
Mol Cell Biol. 20(8):2794-802 (2000) [10733582]

Cross References
Swiss-Prot accessionP29468
SGD YKR002W
Gene Ontology (GO)
Cellular componentGO:0005847mRNA cleavage and polyadenylation specifici...IPI:SGD.
Molecular functionGO:0004652polynucleotide adenylyltransferase activityIDA:SGD.
Biological processGO:0006406mRNA export from nucleusIMP:SGD.
Biological processGO:0006378mRNA polyadenylationIDA:SGD.
EC number 2.7.7.19

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length568
Molecular weight64552

	---------+----------+----------+----------+----------+
MSSQKVFGIT GPVSTVGATA AENKLNDSLI QELKKEGSFE TEQETANRVQ   50
VLKILQELAQ RFVYEVSKKK NMSDGMARDA GGKIFTYGSY RLGVHGPGSD   100
IDTLVVVPKH VTREDFFTVF DSLLRERKEL DEIAPVPDAF VPIIKIKFSG   150
ISIDLICARL DQPQVPLSLT LSDKNLLRNL DEKDLRALNG TRVTDEILEL   200
VPKPNVFRIA LRAIKLWAQR RAVYANIFGF PGGVAWAMLV ARICQLYPNA   250
CSAVILNRFF IILSEWNWPQ PVILKPIEDG PLQVRVWNPK IYAQDRSHRM   300
PVITPAYPSM CATHNITEST KKVILQEFVR GVQITNDIFS NKKSWANLFE   350
KNDFFFRYKF YLEITAYTRG SDEQHLKWSG LVESKVRLLV MKLEVLAGIK   400
IAHPFTKPFE SSYCCPTEDD YEMIQDKYGS HKTETALNAL KLVTDENKEE   450
ESIKDAPKAY LSTMYIGLDF NIENKKEKVD IHIPCTEFVN LCRSFNEDYG   500
DHKVFNLALR FVKGYDLPDE VFDENEKRPS KKSKRKNLDA RHETVKRSKS   550
DAASGDNING TTAAVDVN                                      568