SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard namePAN2
Systematic nameYGL094C
DescriptionPAB-dependent poly(A)-specific ribonuclease subunit PAN2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1         
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (6xHis-Myc-ubiquitin), LC/MS, validation (virtual Western blot)
Reference"Systematic approach for validating the ubiquitinated proteome."
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J.
Anal Chem. 80(11):4161-9 (2008) [18433149]

Cross References
Swiss-Prot accessionP53010
SGD YGL094C
Gene Ontology (GO)
Cellular componentGO:0031251PAN complexIDA:SGD.
Molecular functionGO:0004535poly(A)-specific ribonuclease activityIDA:SGD.
Biological processGO:0031124mRNA 3'-end processingIMP:SGD.
Biological processGO:0006301postreplication repairIGI:SGD.
EC number 3.1.13.4

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length1115
Molecular weight127039

	---------+----------+----------+----------+----------+
MNNWQHFFNN PVDLSEHLKK PYFRFDNRDK EITAISFDEK ANLIWSGDSY   50
GCISSYDPTF QLYTRYRGHI GGNSVKDILS HRDGILSISE DSLHFANRRG   100
VTKLNLTSID IAAFSELNTM CYSPHSLKNN IYCGGDNTNW GIASIDLNRG   150
CLDSLLNYSS KVKLMCSNNK VLSIGRQTGT VDLLDPTSNR TIKSFNAHSA   200
SISAMDLRDN TLVTVGKSKR FYNLYADPFV NVYDLRTMRQ LPPVSFSKGT   250
TMGSGGADFV QLHPLLPTVM IVASSSGSFD FIDLSNPTLR TQYVHPCQSI   300
KKLCLSPNGD VLGILEADNH LDTWRRSSNN MGMFTNTPEM LAYPDYFNDI   350
TSDGPISVDD ETYPLSSVGM PYYLDKLLSA WPPVVFKSEG TIPQLTGKSP   400
LPSSGKLKSN LAVISSQNEK LSTQEFPLLR YDRTKYGMRN AIPDYVCLRD   450
IRKQITSGLE TSDIQTYTSI NKYEVPPAYS RLPLTSGRFG TDNFDFTPFN   500
NTEYSGLDPD VDNHYTNAII QLYRFIPEMF NFVVGCLKDE NFETTLLTDL   550
GYLFDMMERS HGKICSSSNF QASLKSLTDK RQLENGEPQE HLEEYLESLC   600
IRESIEDFNS SESIKRNMPQ KFNRFLLSQL IKEEAQTVNH NITLNQCFGL   650
ETEIRTECSC DHYDTTVKLL PSLSISGINK TVIKQLNKKS NGQNILPYIE   700
YAMKNVTQKN SICPTCGKTE TITQECTVKN LPSVLSLELS LLDTEFSNIR   750
SSKNWLTSEF YGSIIKNKAV LRSTASELKG TSHIFKYELN GYVAKITDNN   800
NETRLVTYVK KYNPKENCFK WLMFNDYLVV EITEEEALKM TYPWKTPEII   850
IYCDAEELRK PFFSVDTYSI NYDILFRDYF ANGIRDTARR EYKLLTHDEA   900
PKSGTLVAID AEFVSLQSEL CEIDHQGIRS IIRPKRTALA RISIIRGEEG   950
ELYGVPFVDD YVVNTNHIED YLTRYSGILP GDLDPEKSTK RLVRRNVVYR   1000
KVWLLMQLGC VFVGHGLNND FKHININVPR NQIRDTAIYF LQGKRYLSLR   1050
YLAYVLLGMN IQEGNHDSIE DAHTALILYK KYLHLKEKAI FEKVLNSVYE   1100
EGRAHNFKVP ETSKG                                         1115