SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


Main Search Enzymes Substrates Ubiquitination types BLAST Feedback HELP

Substrate Information

General Information
Standard nameOST6
Systematic nameYML019W
DescriptionDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ03723
SGD YML019W
Gene Ontology (GO)
Cellular componentGO:0008250oligosaccharyl transferase complexIPI:SGD.
Molecular functionGO:0004579dolichyl-diphosphooligosaccharide-protein g...IPI:SGD.
Biological processGO:0018279protein amino acid N-linked glycosylation v...IGI:SGD.
Biological processGO:0006461protein complex assemblyIMP:SGD.
EC number 2.4.1.119

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length332
Molecular weight37891

	---------+----------+----------+----------+----------+
MKWCSTYIII WLAIIFHKFQ KSTATASHNI DDILQLKDDT GVITVTADNY   50
PLLSRGVPGY FNILYITMRG TNSNGMSCQL CHDFEKTYHA VADVIRSQAP   100
QSLNLFFTVD VNEVPQLVKD LKLQNVPHLV VYPPAESNKQ SQFEWKTSPF   150
YQYSLVPENA ENTLQFGDFL AKILNISITV PQAFNVQEFV YYFVACMVVF   200
IFIKKVILPK VTNKWKLFSM ILSLGILLPS ITGYKFVEMN AIPFIARDAK   250
NRIMYFSGGS GWQFGIEIFS VSLMYIVMSA LSVLLIYVPK ISCVSEKMRG   300
LLSSFLACVL FYFFSYFISC YLIKNPGYPI VF                      332