SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameORM2
Systematic nameYLR350W
DescriptionProtein ORM2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ06144
SGD YLR350W
Gene Ontology (GO)
Cellular componentGO:0005783endoplasmic reticulumIDA:SGD.
Biological processGO:0006986response to unfolded proteinIMP:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)
Residue indexType
9Phosphoserine.
15Phosphoserine.
18Phosphothreonine.

Sequence Information
Sequence length216
Molecular weight24855

	---------+----------+----------+----------+----------+
MIDRTKNESP AFEESPLTPN VSNLKPFPSQ SNKISTPVTD HRRRRSSSVI   50
SHVEQETFED ENDQQMLPNM NATWVDQRGA WLIHIVVIVL LRLFYSLFGS   100
TPKWTWTLTN MTYIIGFYIM FHLVKGTPFD FNGGAYDNLT MWEQINDETL   150
YTPTRKFLLI VPIVLFLISN QYYRNDMTLF LSNLAVTVLI GVVPKLGITH   200
RLRISIPGIT GRAQIS                                        216