SCUD (Saccharomyces Cerevisiae Ubiquitination Database)


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Substrate Information

General Information
Standard nameOPT2
Systematic nameYPR194C
DescriptionOligopeptide transporter 2

Ubiquitination Features
NumberSiteTypeE2E3 ClassE3 SubclassSubstrate ReceptorUbiquitin ReceptorDUBEffect
1        Proteasomal Degradation
* Blank: not determined, NA: not applicable.

References
[1]EvidencePurification & Protein ID
Methodpurification (ubiquitin-chain by UBA domain-containing protein, 6xHis-ubiquitin (two-step)), LC/MS, validation (statistical quantitative analysis)
Reference"Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway."
Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.
Mol Cell Proteomics. 6(11):1885-95 (2007) [17644757]

Cross References
Swiss-Prot accessionQ06593
SGD YPR194C
Gene Ontology (GO)
Cellular componentGO:0005887integral to plasma membraneIC:SGD.
Molecular functionGO:0015198oligopeptide transporter activityIDA:SGD.
Molecular functionGO:0005515protein bindingIPI:IntAct.
Biological processGO:0006857oligopeptide transportIDA:SGD.
EC number  

Additional Features
Other Post Translational Modifications (PTM)  

Sequence Information
Sequence length877
Molecular weight101261

	---------+----------+----------+----------+----------+
MSETVKDKVI IDEKVSTKGT VDYAEGAEYS ERLSNHSSDF SQWYTDEQIL   50
HFMKKLGYEN RTLYDIPEDV AYILKKMPEL TLEDSFKILK DSIIYFKDDE   100
NIPHDQYEEW KRLVDLEDLD SKEGIDEYDS FDIRAFASAI KFHSPYQEVR   150
AVVDPEDDPT IPVETFRAYF LAIIWSVIGS GFNEFFSHRV VSISLNTPII   200
QMFLYICGKA WAKTIPCWTI TIRGRKYGIN IDKPWTQKEQ MFSTLLYAIC   250
QGAFYTHYNI LTQKLFYHSA FSFGYQFLLS LSVQFIGFGF AGILRKFVVY   300
PARALWPTVM PTIAINKALL GKEKHESGMS RYKFFFLTFF IMFIYNWFPT   350
YIINILNTFN WMTWIKPSNI NLANITGGVT GLGINPISSF DWNVISFNSP   400
LVYPFWSYLT QYLGCILAAL IVIAVYYSNY MSCQYLPIFT NSLYTNTGHS   450
FKVTEVLDSD NKLDVKKYQS YSPPYYSAGN LVSYGAFICA YPLMITWSFI   500
VHSKLLFNAF KDWALNLWAM RKLKSWVTMF KSDYRALDDY DDPHSNAMKN   550
YKEVPDWWYF AILIGSLVVG IAVVEHYPTN TPVWGLFVCL GFNFVFLIPT   600
TILQATTGYS FGLNLLIEMV MGYALPGNPI AIMILKAFGY NIDGQADNYV   650
SNLKIAHYCK IPPMALFRGQ CVIVFIQIFV NLGVLNWQIS NIKDFCTPHQ   700
NAKFTCPDAV TYYNASVVWG AIGPKRIFNY IYPIFKWCWL IGACIGIFFG   750
VWKRWGKFYP RYFDPMLFVG GMLNMSPPYN LMYYTSGMIV SYISQYYMKR   800
HHLNLWEKYN YVLSAGFSTG LVLSAIIIFF AVQYKDTAFN WWGNTVPYAG   850
ADGVGYPLKN ITDTANGYFG YAPGHYP                            877